Yearly Archives: 2011

/Publication/
17 11, 2011

Synthesis of (Glycopyranosyl-triazolyl)-purines and Their Inhibitory Activities against Protein Tyrosine Phosphatase 1B (PTP1B)

Lei Luo, Xiao-Peng He, Qiang Shen, Jing-Ya Li, Xiao-Xin Shi, Juan Xie*, Jia Li*, Guo-Rong Chen*

Chem. Biodiversity 2011, 8, 2035-2044. DOI 10.1002/cbdv.201000242

16 10, 2011

Synthesis of Triazole-Linked Amino Acid-Aryl C-Glycoside Hybrids via Click Chemistry as Novel PTP1B Inhibitors.

Jia Wang, Xiaopeng He, Lixin Gao, Li Sheng, Xiaoxin Shi, Jia Li*, Guorong Chen*

Chin. J. Chem. 2011, 29, 1227-1232.. DOI 10.1002/chin.201146185

15 10, 2011

Discovery of a sensitive Cu(ii)-cyanide “off–on” sensor based on new C-glycosyl triazolyl bis-amino acid scaffold

Yan-Hui Tang, Yi Qu, Zhuo Song, Xiao-Peng He*, Juan Xie, Jianli Hua*, Guo-Rong Chen*

Org. Biomol. Chem. 2011, 10, 555-560. DOI 10.1039/c1ob06242e

14 09, 2011

Click to a focused library of benzyl 6-triazolo(hydroxy)benzoic glucosides: Novel construction of PTP1B inhibitors on a sugar scaffold

Cui Li, Xiao-Peng He, Yin-Jie Zhang, Zhen Li, Li-Xin Gao, Xiao-Xin Shi, Juan Xie, Jia Li*, Guo-Rong Chen*, Yun Tang*

Eur. J. Med. Chem. 2011, 46, 4212-4218. DOI 10.1016/j.ejmech.2011.06.025

13 09, 2011

Discovering the distinct inhibitory effects between C4-epimeric glycosyl amino acids: new insight into the development of protein tyrosine phosphatase inhibitors

Xiao-Peng He, Cui Li, Zhi-Zhou Wang, Li-Xin Gao, Xiao-Xin Shi, Yun Tang, Juan Xie*, Jia Li*, Guo-Rong Chen*, Kaixian Chen

Glyconj. J. 2011, 28, 493-497. DOI 10.1007/s10719-011-9347-0

12 08, 2011

Disclosing the distinct interfacial behaviors of structurally and configurationally diverse triazologlycolipids

Xiao-Peng He, Xiaolian Xu, Hai-Lin Zhang, Guo-Rong Chen*, Shouhong Xu*, Honglai Liu

Carbohydr. Res. 2011, 346, 1320-1326. DOI 10.1016/j.carres.2011.04.038

11 07, 2011

Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on ‘clicked’ serine/threonine–monosaccharide hybrids

Xiao-Peng He, Qiong Deng, Li-Xin Gao, Cui Li, Wei Zhang, Yu-Bo Zhou, Yun Tang, Xiao-Xin Shi, Juan Xie*, Jia Li*, Guo-Rong Chen*, Kaixian Chen

Bioorg. Med. Chem. Lett. 2011, 19, 3892-3900. DOI 10.1016/j.bmc.2011.05.049

10 06, 2011

6-O-Amino-2-O-carboxymethyl Glucopyranoside as Novel Glycoaminoxy Acid Building Block for the Construction of Oligosaccharide Mimetics

Zhuo Song, Xiao-Peng He, Guo-Rong Chen*, Juan Xie*

Synthesis 2011, 17, 2761-2766. DOI 10.1055/s-0030-1260139

9 06, 2011

Synthesis of novel 6-triazologlycolipids via click chemistry and their preliminary cytotoxicity assessments

Hai-Lin Zhang, Xiao-Peng He, Li Sheng, Yuan Yao, Wei Zhang, Xiao-Xin Shi, Jia Li*, Guo-Rong Chen*

Mol. Divers. 2011, 15, 889-900. DOI 10.1007/s11030-011-9318-1

8 05, 2011

Creation of 3,4-bis-triazolocoumarin–sugar conjugates via flourogenic dual click chemistry and their quenching specificity with silver(I) in aqueous media

Xiao-Peng He, Zhuo Song, Zhi-Zhou Wang, Xiao-Xin Shi*, Kaixian Chen*, Guo-Rong Chen*

Tetrahedron 2011, 67, 3343-3347. DOI 10.1016/j.tet.2011.03.068